You could be based in a university, combining chemical research with teaching; working on developing and trialing new drugs; or helping to ensure national healthcare provision keeps pace with new discoveries. 14489-75-9, Name is N-Methyl-1-(naphthalen-1-yl)methanamine, molecular formula is C12H13N, belongs to isothiazole compound. In a document, author is Yang, XP, introduce the new discover, Product Details of 14489-75-9.
To look for novel compounds with biological activity, 3-arylsulfonyloxy (substituted) isothiazoles were synthesized by the condensation of 3-hydroxy (substituted) isothiazoles with arylsulfonylchlorides in the presence of base. The structures of target compounds were confirmed by elemental analysis, H-1 NMR, IR, MS. Also, the single crystal structures of compounds 3c and 4b were determined, All the facts ascertained that the sulfonylization position was oxygen atom of isothiazole heterocycle. The herbicidal activities of title compounds were determined and the result showed that it was possible that they were ALS inhibitors.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com