Recommanded Product: 2,6-Dimethoxyphenol, Some examples of the diverse research done by chemistry experts include discovery of new medicines and vaccines, improving understanding of environmental issues, and development of new chemical products and materials. 91-10-1, Name is 2,6-Dimethoxyphenol, SMILES is COC1=CC=CC(OC)=C1O, belongs to isothiazole compound. In a article, author is Fisher, Matthew J., introduce new discover of the category.
The disclosed 3-phenyl-5-isothiazole carboxamides are potent allosteric antagonists of mGluR1 with generally good selectivity relative to the related group 1 receptor mGluR5. Pharmacokinetic properties of a member of this series (1R,2R)-N-(3-(4-methoxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropanecarboxamide (14) are good, showing acceptable plasma and brain exposure after oral dosing. Oral administration of isothiazole 14 gave robust activity in the formalin model of persistent pain which correlated with CNS receptor occupancy. (C) 2012 Elsevier Ltd. All rights reserved.
Recommanded Product: 2,6-Dimethoxyphenol, Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. I hope my blog about 91-10-1 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com