Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment. 92-91-1, Name is 1-([1,1′-Biphenyl]-4-yl)ethanone, molecular formula is C14H12O, Category: isothiazole, belongs to isothiazole compound, is a common compound. In a patnet, author is Mares, D, once mentioned the new application about 92-91-1.
The antifungal activity of 4-amino-3-methyl-1 -phenylpyrazolo-(3,4-c)isothiazole was studied on Trichophyton rubrum. The compound, at concentrations between 20 and 100 mu g ml(-1), induces a remarkable reduction in the growth and causes deep morphogenetic anomalies. The ultrastructural modifications have demonstrated that the compound targets the cell membrane of the fungus, breaking down not only the endomembrane system, but also the ‘outer’ membrane, with consequent extrusion of materials in the medium. The results suggests a mechanism of action similar to other azoles clinically utilized.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 92-91-1 is helpful to your research. Category: isothiazole.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com