Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 3466-32-8, Name is 1-Bromo-4-(methylsulfonyl)benzene, molecular formula is C7H7BrO2S, Quality Control of 1-Bromo-4-(methylsulfonyl)benzene, belongs to isothiazole compound, is a common compound. In a patnet, author is Atobe, Masakazu, once mentioned the new application about 3466-32-8.
A series of 1,1-dioxothieno[2,3-d]isothiazole (thienosultam) derivatives were designed and synthesized as novel ADAMTS-5 inhibitors for an investigation into a side chain of thienosultam for the S1′ pocket. The resulting compounds (19 and 24) show high ADAMTS-5 inhibition and other MMP selectivity, and these compounds show good oral bioavailability. (C) 2013 Elsevier Ltd. All rights reserved.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com