HPLC of Formula: https://www.ambeed.com/products/53242-76-5.html, Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play. 53242-76-5, Name is 2-(2-(4-Chlorophenyl)acetyl)benzoic acid, SMILES is O=C(O)C1=CC=CC=C1C(CC2=CC=C(Cl)C=C2)=O, belongs to isothiazole compound. In a article, author is Regiec, A., introduce new discover of the category.
The main goal of our study was the synthesis and biological evaluation of 4-amino- and 4-[(4-chlorobenzoyl)amino]-1-methylimidazole N-substituted 5-carboxamides. Biological in vitro tests indicated their remarkable influence on some cellular immune and inflammatory responses compared with ibuprofen and leflunomide as reference drugs. The toxicity of the tested compounds on murine bone marrow cells was also determined. The anti-inflammatory activity of 4-[(4-chlorobenzoyl)amino]-5-[N-(4-chlorophenyl)]-1-methyl-5-imidazolecarboxamide (7a) was confirmed in vivo in the carrageenan-induced oedema test. Comparison of the biological activity of 7a with that of the isosteric isothiazole derivative MR-2/94 suggests that replacement of the isothiazole core ring system with an imidazole one resulted in a considerable lowering of toxicity while maintaining anti-inflammatory and immunotropic properties.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 53242-76-5 is helpful to your research. HPLC of Formula: https://www.ambeed.com/products/53242-76-5.html.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com