Chemical research careers are more diverse than they might first appear, as there are many different reasons to conduct research and many possible environments. 53242-76-5, Name is 2-(2-(4-Chlorophenyl)acetyl)benzoic acid, SMILES is O=C(O)C1=CC=CC=C1C(CC2=CC=C(Cl)C=C2)=O, in an article , author is Kletskov, Alexey V., once mentioned of 53242-76-5, Application of 53242-76-5.
Methyl 5-hydroxy-4-oxo-4H-pyran-2-carboxylate was synthesized by esterification of methanol with comenic acid under acidic catalysis. The obtained ester was alkylated with 3-(chloromethyl)-5-phenylisoxazole and 4,5-dichloro-3-(chloromethyl)isothiazole to afford corresponding conjugates containing isoxazole and isothiazole moieties which then were transformed into water-soluble Li-salts. During the bioassays of synthesized isoxazole and isothiazole derivatives of comenic acid in mixtures with first-line antitumor drug Temobel (Temozolomid) used in brain tumors chemotherapy, a synergetic effect was observed.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 53242-76-5. Application of 53242-76-5.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com