While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards. 22884-95-3, Name is 3,4-Dimethylbenzonitrile, molecular formula is C9H9N, belongs to isothiazole compound. In a document, author is Li, Meng-Fan, introduce the new discover, Name: 3,4-Dimethylbenzonitrile.
The combination of Pd(TFA)(2) and an N,N’-disulfonyl bisimidazoline ligand shows high catalytic activity and excellent asymmetric induction in the addition of arylboronic acids to cyclic N-sulfonyl ketimines including benzo[d]-isothiazole-1,1-dioxides, benzo[e][1,2,3]oxathiazine-2,2-dioxides, and 1,2,5-thiadiazole-1,1-dioxides, by which three types of chiral quaternary carbon-containing sultams with substantial substitution diversity were synthesized with high yields and excellent enantioselectivities (up to >99% ee). The current catalysis demonstrated a remarkable tolerance to oxygen and thus provided an operationally simple approach for constructing enantioenriched cyclic quaternary stereocenters.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 22884-95-3. Name: 3,4-Dimethylbenzonitrile.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com