Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment. 455-19-6, Name is 1-Formyl-4-trifluoromethylbenzene, molecular formula is C8H5F3O, Electric Literature of 455-19-6, belongs to isothiazole compound, is a common compound. In a patnet, author is Clerici, F, once mentioned the new application about 455-19-6.
3-Diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide(1) was made to react with arylalkyl- and arylazides 2. Cycloadducts 3, which could he isolated in some cases, afforded N-arylalkyl or N-aryl-thiadiazabicyclo[3.1.0]hexene derivatives 4 through N-2-elimination. Thermal rearrangements of N-aryl- and N-beta-phenylethyl substituted compounds 4b-e, produced derivatives of 1,2-thiazete 1,1-dioxide 5, 1,2,6-thiadiazine 1,1-dioxide 6 and pyrazole 7. The reaction can be optimized to afford compounds 6 in synthetically useful yield. In the case of N-benzyl-thiadiazabicyclo[3.1.0]hexene derivative 4a the different substitution on the aziridine nitrogen produced a different reaction course, affording the thiadiazine derivative 6a and the pyrimidine derivative 8. Copyright (C) 1996 Elsevier Science Ltd
I am very proud of our efforts over the past few months and hope to 455-19-6 help many people in the next few years. Electric Literature of 455-19-6.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com