New Advances in Chemical Research, April 2021. Synthetic Route of 393-11-3, Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. 393-11-3, Name is 4-Nitro-3-(trifluoromethyl)aniline, SMILES is C1=C(N)C=CC(=C1C(F)(F)F)[N+]([O-])=O, belongs to isothiazole compound. In a article, author is Dobrydnev, Alexey V., introduce new discover of the category.
A range of aminonitriles, readily available by Strecker reaction, were forced to react with methyl 2-(chlorosulfonyl) acetate. Methyl 2-[[(cyanoalkyl) amino] sulfonyl] acetates formed on the first stage without isolation were converted to methyl 4-amino-2,3,3-trisubstituted-1,1-dioxo-2,3-dihydro-1H-1 lambda(6) -isothiazole-5-carboxylates via CSIC reaction using Et3N-mediated conditions in poor to high yields. The structure of the target compound was confirmed by X-ray diffraction study.
Synthetic Route of 393-11-3, Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.I hope my blog about 393-11-3 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com