New Advances in Chemical Research in 2021. Safety of 3-(4-Chlorophenyl)pentanedioic acid, You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. 35271-74-0, Name is 3-(4-Chlorophenyl)pentanedioic acid, SMILES is O=C(O)CC(C1=CC=C(Cl)C=C1)CC(O)=O, belongs to isothiazole compound. In a article, author is Rodina, L. L., introduce new discover of the category.
It has been established that the interaction of diazomethane with 4,5-dialkyl-substituted 3-oxo-(2H)-isothiazole 1,1-dioxides proceeds in two stages. Initially alkylation of the sulfonimide nitrogen atom and the carbonyl group oxygen atom occurs (in a ratio of similar to 3:2), then there is a regioselective cycloaddition of diazomethane at the C=C double bond with the formation of the corresponding N-methyloxoisothiazolopyrazolines and 3-methoxyisothiazolopyrazolines.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 35271-74-0, Safety of 3-(4-Chlorophenyl)pentanedioic acid.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com