New Advances in Chemical Research, April 2021. Formula: https://www.ambeed.com/products/1504-58-1.html, Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment.1504-58-1, Name is 3-Phenylprop-2-yn-1-ol, SMILES is OCC#CC1=CC=CC=C1, belongs to isothiazole compound. In a article, author is Moon, Sanghun, introduce new discover of the category.
A rhodium-catalyzed oxidative annulation of benzimidates with elemental sulfur for the direct construction of isothiazole rings is reported. The proposed reaction mechanism involving Rh(I)/Rh(III) redox is supported by a stoichiometric reaction of metallacycle species as well as DFT calculations. This method is also applicable to selenium cyclization to produce isoselenazole derivatives. The alkoxy substituent at C3 can be used for further functionalization of the azole core.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 1504-58-1, Formula: https://www.ambeed.com/products/1504-58-1.html.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com