Chemical Research Letters, April 2021. With the volume and accessibility of scientific research increasing across the world, it has never been more important to continue building the reputation we’ve spent the past two centuries establishing. 58446-52-9, Name is 1-Phenylicosane-1,3-dione, molecular formula is C26H42O2, Safety of 1-Phenylicosane-1,3-dione, belongs to isothiazole compound, is a common compound. In a patnet, author is CLERICI, F, once mentioned the new application about 58446-52-9.
N-alkylsulfonylamidines of alpha-ketoacids 3 bearing both a carbonyl group and at least one H-atom near to the SO2 group give easily an intramolecular ring-closure reaction by action of potassium t-butoxide producing the 3-amino-4,5-dihydro-4-hydroxy-isothiazole S,S-dioxides 4. Compounds 4 are transformed by thionyl chloride into the corresponding chloro-derivatives 5 which in turn are dehydrochlorinated by potassium carbonate to substituted 3-amino-isothiazole S,S-dioxides 6.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 58446-52-9, Safety of 1-Phenylicosane-1,3-dione.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com