New Advances in Chemical Research, April 2021. COA of Formula: https://www.ambeed.com/products/1504-58-1.html, Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. 1504-58-1, Name is 3-Phenylprop-2-yn-1-ol, SMILES is OCC#CC1=CC=CC=C1, belongs to isothiazole compound. In a article, author is Lippa, B, introduce new discover of the category.
The design, synthesis, and biological evaluation of potent inhibitors of the TrkA kinase is presented. A homology model is created to aid in the enhancement of potency and selectivity of isothiazole inhibitors found during a high-throughput screen. Three different syntheses are utilized to make diverse analogs within this series. Aminoheterocycles are found to be good urea surrogates, whereas bicyclic substituents on the C3 thio group were found to be extremely potent TrkA inhibitors in kinase and cell assays. (c) 2006 Elsevier Ltd. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 1504-58-1. COA of Formula: https://www.ambeed.com/products/1504-58-1.html.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com