New discoveries in chemical research and development in 2021, Chemistry involves the study of all things chemical – chemical processes, how they change and how they react in certain situations. 35285-69-9, Name is Sodium 4-(propoxycarbonyl)phenolate, SMILES is [O-]C1=CC=C(C(OCCC)=O)C=C1.[Na+], in an article , author is Lippa, B, once mentioned of 35285-69-9, Recommanded Product: Sodium 4-(propoxycarbonyl)phenolate.
The design, synthesis, and biological evaluation of potent inhibitors of the TrkA kinase is presented. A homology model is created to aid in the enhancement of potency and selectivity of isothiazole inhibitors found during a high-throughput screen. Three different syntheses are utilized to make diverse analogs within this series. Aminoheterocycles are found to be good urea surrogates, whereas bicyclic substituents on the C3 thio group were found to be extremely potent TrkA inhibitors in kinase and cell assays. (c) 2006 Elsevier Ltd. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 35285-69-9. Recommanded Product: Sodium 4-(propoxycarbonyl)phenolate.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com