Chemical Research Letters, April 2021. Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 555-16-8, Name is 4-Nitrobenzaldehyde, molecular formula is C7H5NO3, Reference of 555-16-8, belongs to isothiazole compound, is a common compound. In a patnet, author is CARUGO, O, once mentioned the new application about 555-16-8.
3-Diethylamino-4-(4-methoxyphenyl)-isothiazole-1,1-dioxide 1, was reacted with the azide ion in different solvents. Depending on reaction conditions 4-diethylamino-3a,6a-dihydro-3a-(4-methoxyphenyl)-1H-isothiazole-[4,5-d]-1,2,3-triazole-6,6-dioxide 3 and/or 4-diethylamino-1-[3-diethylamino-4,5-dihydro-4-(4-methoxyphenyl)-5-isothiazolyl-1,1-dioxide]-3a,6a-dihydro-3a-(4-methoxyphenyl)-1H-isothiazole-[4,5-d]- 1,2,3- triazole-6,6-dioxide 4 were formed. When ethanol or acetone were used as reaction solvent the formation of the above compounds was accompanied by solvent addition forming 3-diethylamino-4,5-dihydro-4-(4-methoxyphenyl)-5-ethoxy-isothiazole-1,1-dioxide 2 and 3-diethylamino-4,5-dihydro-4-(4-methoxyphenyl)-5-(2-oxopropyl)-isothiazole-1,1-dioxide 6, respectively. Reaction mechanisms and structures of products are discussed.
Reference of 555-16-8, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect. I hope my blog about 555-16-8 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com