Chemical Research Letters, April 2021. Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. 459-56-3, Name is (4-Fluorophenyl)methanol, molecular formula is C7H7FO, Application In Synthesis of (4-Fluorophenyl)methanol, belongs to isothiazole compound, is a common compound. In a patnet, author is Noack, A, once mentioned the new application about 459-56-3.
4,5-Disubstituted N-phenyl-isothiazolium salts 1 with active 5-methyl group react under the influence of anilines to form 3,4-disubstituted isothiazolium salts 3. The influence of donor and acceptor substituents in the 2-phenyl group of 1a-h and in the anilines 2 on the ring transformation were studied. The structure of the new salts was confirmed by X-ray analysis. The 3-hydroperoxy-2,3-dihydro-isothiazole 1,1-dioxides (12a,d)and the isothiazole-3(2H) -one 1,1-dioxides (14a,d) are obtained by oxidation of salts 3 with H2O2.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 459-56-3. Application In Synthesis of (4-Fluorophenyl)methanol.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com