New Advances in Chemical Research, April 2021. SDS of cas: 151-05-3, Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. 151-05-3, Name is 2-Methyl-1-phenylpropan-2-yl acetate, SMILES is CC(OC(C)(C)CC1=CC=CC=C1)=O, belongs to isothiazole compound. In a article, author is Fisher, Matthew J., introduce new discover of the category.
The disclosed 3-phenyl-5-isothiazole carboxamides are potent allosteric antagonists of mGluR1 with generally good selectivity relative to the related group 1 receptor mGluR5. Pharmacokinetic properties of a member of this series (1R,2R)-N-(3-(4-methoxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropanecarboxamide (14) are good, showing acceptable plasma and brain exposure after oral dosing. Oral administration of isothiazole 14 gave robust activity in the formalin model of persistent pain which correlated with CNS receptor occupancy. (C) 2012 Elsevier Ltd. All rights reserved.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 151-05-3, SDS of cas: 151-05-3.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com