Chemical Research Letters, April 2021. Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 2051-95-8, Name is 3-Benzoylpropionicacid, molecular formula is C10H10O3, Category: isothiazole, belongs to isothiazole compound, is a common compound. In a patnet, author is LASNE, MC, once mentioned the new application about 2051-95-8.
2-[3-(4-(4[F-18]Fluorophenyl)-1-piperazinyl)propyl]-2H-naphth[1,8-cd]isothiazole-1,1-dioxide] ([F-18]RP 62203), an antagonist of 5-HT2 receptors, was prepared from [F-18]fluoride via a 3-step reaction sequence, with an overall radiochemical yield of 5-12% (decay corrected) and within 190-230 min (total automated synthesis from EOB). The key step involved the rapid (6 min, 150 degrees C in octanol) and efficient (> 65%) reaction of an appropriate bis(bromoethyl)amine derivative with 4-[F-18]fluoroaniline.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2051-95-8. Category: isothiazole.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com