Chemical Research Letters, April 2021. Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 611-70-1, Name is Isobutyrophenone, molecular formula is C10H12O, Quality Control of Isobutyrophenone, belongs to isothiazole compound, is a common compound. In a patnet, author is Kletskov, Alexey V., once mentioned the new application about 611-70-1.
The chemistry of isothiazoles is being intensively developed, which is evidenced by the wide range of selective transformations involving the isothiazole heterocycle and the high biological activity of its derivatives that can be used as effective new drugs and plant protection chemicals. Some representatives of isothiazoles have proven to be synergists of bioactive substances, which opens the way to lower the doses of drugs used and is especially important in cancer chemotherapy. In the framework of the present review, the accomplishments in the chemistry of isothiazoles over the past 18 years are examined, whilst current strategies for the synthesis of isothiazole-containing molecules and key directions of studies in this field of heterocyclic chemistry are discussed. Considerable attention is paid to chlorinated isothiazoles and strategies for their use in the synthesis of biologically active substances. In addition, a comprehensive review of existing literature in the field of metal complexes of isothiazoles is given, including the results and prospects for the practical use of isothiazole-metal complexes as catalysts for cross-coupling reactions in aqueous and aqueous-alcoholic media (‘green chemistry’). 1 Introduction 2 Synthesis by Ring-Forming Reactions 2.1 Intramolecular Cyclization 2.2 (4+1)-Heterocyclization 2.3 (3+2)-Heterocyclization 2.4 Syntheses by Ring Transformations 3 Isothiazoles by Ring Functionalization Reactions: Nucleophilic Substitution, Cross-Coupling and Side-Chain Functionalization 4 Selected Syntheses of Biologically Active Isothiazole Derivatives 5 Isothiazoles in the Synthesis of Transition-Metal Complexes and in Metal-Complex Catalysis 6 Conclusion
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 611-70-1. Quality Control of Isobutyrophenone.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com