New Advances in Chemical Research in 2021. Formula: https://www.ambeed.com/products/80-07-9.html, You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. 80-07-9, Name is 4,4′-Sulfonylbis(chlorobenzene), SMILES is O=S(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)=O, belongs to isothiazole compound. In a article, author is Barchiesi, F, introduce new discover of the category.
We investigated the activity of a pyrazolo-isothiazole derivative (G8) against Cryptococcus neoformans. A first screening test showed that G8 at 10 mg/L inhibited the growth of 14 of 15 clinical isolates tested. Killing experiments showed that fungicidal activity was achieved after 8 h of treatment with G8 at concentrations greater than or equal to10 mg/L. In a murine model of systemic cryptococcosis, G8 was effective at prolonging survival compared with the controls. Our data indicate that this new derivative has a potential therapeutic role in infections caused by C. neoformans.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. Interested yet? Keep reading other articles of 80-07-9, you can contact me at any time and look forward to more communication. Formula: https://www.ambeed.com/products/80-07-9.html.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com