Chemical Research Letters, April 2021. Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. 495-40-9, Name is 1-Phenylbutan-1-one, molecular formula is C10H12O, Computed Properties of https://www.ambeed.com/products/495-40-9.html, belongs to isothiazole compound, is a common compound. In a patnet, author is Soler, Lucia, once mentioned the new application about 495-40-9.
The alkylation of sodium saccharin with alkyl halides to produce the intermediates.-( 1,1,3-trioxo-1,3-dihydrobenzo[d]isothiazol-2-yl)-alkanecarboxylic acids can be markedly improved by using microwave irradiation, both in terms of product yield and reaction time. While the process produces high yields with halo esters and halonitriles, the reaction with haloacids, which proceeds smoothly by conventional reflux, gives poorer yields with microwaves. This is due to an acid-base equilibrium produced by the rapid heating of the mixture under irradiation. Esters and nitriles can be converted into the acids by acid hydrolysis, without appreciable loss of the 1,1,3-trioxo-1,3-dihydrobenzo[ d] isothiazole ring.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 495-40-9, Computed Properties of https://www.ambeed.com/products/495-40-9.html.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com