As a common heterocyclic compound, it belongs to isothiazole compound, name is 3-Piperazinobenzisothiazole hydrochloride, and cas is 87691-88-1, its synthesis route is as follows.
To a solution of N- [5-CHLORO-4- (2-CHLORO-ACETYL)-2-METHYL-PHENYL]- acetamide (1.375 g, 5.286 mmol), in acetonitrile (50 mL) was added 3- PIPERAZIN-1-YL-BENZO [d] isothiazole hydrochloride (1.352 g, 5.286 mmol), potassium iodide (1EQ), and potassium carbonate (1.5eq). The reaction was stirred as a suspension at rt overnight. The reaction was diluted with H20 and the filtered. After drying at 50 C under high vacuum overnight, N- {4- [2- (4-BENZO [d] isothiazol-3-yl-peperazin-1-yl)-acetyl]-5-chloro-2- METHYL-PHENYL)-ACETAMIDE was collected as a white solid (2.034 g, 4.598 mmol). Yield = 87%. 100% pure at 254 nM; LCMS (APCI) : 443.3 [M+H] + ; ‘H NMR (400 MHz, DMSO-d6) B 9.41 (s, 1H), 8.02 (d, J = 8. 80HZ, 2H), 7.81 (s, 1H), 7.59 (s, 1H), 7.52 (t, J = 7.34Hz, 1H), 7.39 (t, J = 7.34Hz, 1H), 3.80 (s, 2H), 3.44-3. 37 (m, 4H), 3.30 (s, H20), 2.77-2. 68 (m, 4H), 2.23 (s, 3H), 2.08 (s, 3H).
87691-88-1, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,87691-88-1 ,3-Piperazinobenzisothiazole hydrochloride, other downstream synthetic routes, hurry up and to see
Reference：
Patent; WARNER-LAMBERT COMPANY LLC; WO2004/41793; (2004); A1;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com