Chemical Research Letters, April 2021. Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 14489-75-9, Name is N-Methyl-1-(naphthalen-1-yl)methanamine, molecular formula is C12H13N, Recommanded Product: 14489-75-9, belongs to isothiazole compound, is a common compound. In a patnet, author is Kunugi, A, once mentioned the new application about 14489-75-9.
The introduction of sulfur atoms into trifluoromethylated alkenyl sulfones and chlorides were studied using a reactive sulfur-graphite electrode in N,N-dimethylformamide. A substrate, 2-(4-biphenylyl)-4,4,4-trifluoro-3-phenylsulfonyl-2-butenenitrile (1a) afforded a coupling compound bridged with a nitrogen atom of isothiazole and 1,2-dithiolane skeleton (2). 1-(4-Biphenylyl)-3,3,3-trifluoro-2-phenylsulfonylpropene (1b) without a cyano group gave a complex oligomeric compound (3) without the elimination of the phenylsulfonyl group. 2- (4-Biphenylyl)-3-chloro-4,4,4-trifluoro-2 butenenitrile (1c) having a chloro group as a leaving group gave 2,4-di (4-biphenylyl)-2,4-dicyano-1,5-bis (trifluoromethyl)-3,6-dithiabicyclo[3.1.0]hexane (4) and 2-(4-biphenylyl)-4,4,4-trifluoro-2-butenenitrile (5). Methyl 2-(4- biphenylyl)-3-chloro-4,4,4-trifluoro-2-butenoate (1d) having an ester group in the place of a cyano group afforded di-[2-(4 biphenylyl)-2-methoxycarbonyl-1 trifluoromethylethyl] disulfide (6). The formation of such sulfur-containing organofluorine compounds except for the oligomeric compound 3 is characterized as the addition of polysulfide anion(s) produced by electroreduction of elemental sulfur. followed by the elimination of the phenylsulfonyl or the chloro group.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 14489-75-9, Recommanded Product: 14489-75-9.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com