New research progress on 103-60-6 in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 103-60-6, Name is 2-Phenoxyethyl isobutyrate, formurla is C12H16O3. In a document, author is MALLERON, JL, introducing its new discovery. Application In Synthesis of 2-Phenoxyethyl isobutyrate.
A series of 2-(aminoalkyl)naphth[1,8-cd]isothiazole 1,1-dioxides was synthesized and examined in various receptor binding tests. Most compounds demonstrated high affinity for the 5-HT2 receptor with moderate to high selectivity. A member of this series, compound 24 (RP 62203), displays high 5-HT2 receptor affinity (K(i) = 0.26 nM), which is respectively more than 100 and 1000 times higher than its affinity for alpha-1 (K(i) = 38 nM) and D2 (K(i) > 1000 nM) receptors. This compound is a potent orally effective and long lasting 5-HT2 antagonist in the mescaline-induced head-twitches test in mice and rats.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 103-60-6, Application In Synthesis of 2-Phenoxyethyl isobutyrate.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com