New Advances in Chemical Research, April 2021. Related Products of 385-00-2, In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. The reactant in an enzyme-catalyzed reaction is called a substrate. 385-00-2, Name is 2,6-Difluorobenzoic acid, SMILES is O=C(O)C1=C(F)C=CC=C1F, belongs to isothiazole compound. In a article, author is Omelian, Taras, V, introduce new discover of the category.
We report a strategy for the construction of tetrahydro-1H-1(6)-pyrrolo[1,2-b]isothiazole-1,1,3(2H)-triones bearing the substituents at the 5- and/or 3a-positions. To this purpose, a range of 2-substituted and 2,4-disubstituted methyl 2-pyrrolidinecarboxylates were sulfonylated with methanesulfonyl chloride and the resulting sulfonamides were subjected to sulfa-Dieckmann condensation through the CSIC (Carbanion mediated Sulfonate (Sulfonamido) Intramolecular Cyclization) reaction to give the desired 1(6)-isothiazolidine-1,1,4-triones. All the precursors, as well as target compounds, could be synthesized in a multigram scale following the general protocols.
Related Products of 385-00-2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect. I hope my blog about 385-00-2 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com