New discoveries in chemical research and development in 2021, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 827-25-8, Name is 2-Bromo-4-chloro-6-nitrophenylamine, SMILES is BrC1=C(C(=CC(=C1)Cl)[N+](=O)[O-])N, in an article , author is Liu, ZP, once mentioned of 827-25-8, Safety of 2-Bromo-4-chloro-6-nitrophenylamine.
o-Lithiation of N-tert-butylbenzenesulfonamide followed by reaction with ketones gave carbinol sulfonamides, which underwent TMSCl-NaI-MeCN reagent mediated cyclization to afford 3,3-disubstituted and spiro-2,3-dihydrobenzo[d] isothiazole-1,1-diones in high yields.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 827-25-8. Safety of 2-Bromo-4-chloro-6-nitrophenylamine.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com