New Advances in Chemical Research in 2021, Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media. 1504-58-1, Name is 3-Phenylprop-2-yn-1-ol, molecular formula is C9H8O, belongs to isothiazole compound. In a document, author is Lippa, B, introduce the new discover, Name: 3-Phenylprop-2-yn-1-ol.
The design, synthesis, and biological evaluation of potent inhibitors of the TrkA kinase is presented. A homology model is created to aid in the enhancement of potency and selectivity of isothiazole inhibitors found during a high-throughput screen. Three different syntheses are utilized to make diverse analogs within this series. Aminoheterocycles are found to be good urea surrogates, whereas bicyclic substituents on the C3 thio group were found to be extremely potent TrkA inhibitors in kinase and cell assays. (c) 2006 Elsevier Ltd. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 1504-58-1. Name: 3-Phenylprop-2-yn-1-ol.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com