Chemical Research Letters, April 2021. Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 2144-08-3, Name is 2,3,4-Trihydroxybenzaldehyde, molecular formula is C7H6O4, Safety of 2,3,4-Trihydroxybenzaldehyde, belongs to isothiazole compound, is a common compound. In a patnet, author is STRATMANN, K, once mentioned the new application about 2144-08-3.
Aulosirazole, the major cytotoxin in the blue-green alga (cyanobacterium) Aulosira fertilissima Ghose (UH strain DO-8-1), shows solid tumor selective activity in the Corbett assay. Its structure has been determined to be 5-hydroxy-3-methoxynaphtho[2,3-d]-1,2-thiazole-4,9-dione by a combination of spectroscopic, notably NMR, and X-ray crystallographic methods. The carbon skeleton and the juglone nature of 1 was determined by two-dimensional H-1-C-13 NMR correlation spectral analysis and one-dimensional C-13-C-13 decoupling experiments, the latter on the C-13-enriched cytotoxin. The presence of an isothiazole ring and the position of attachment for the juglone system was rigorously established by an X-ray crystallographic study.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 2144-08-3, Safety of 2,3,4-Trihydroxybenzaldehyde.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com