New research progress on 29679-58-1 in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 29679-58-1, Name is 2-(3-Phenoxyphenyl)propanoic acid, formurla is C15H14O3. In a document, author is MALLERON, JL, introducing its new discovery. Computed Properties of https://www.ambeed.com/products/29679-58-1.html.
A series of 2-(aminoalkyl)naphth[1,8-cd]isothiazole 1,1-dioxides was synthesized and examined in various receptor binding tests. Most compounds demonstrated high affinity for the 5-HT2 receptor with moderate to high selectivity. A member of this series, compound 24 (RP 62203), displays high 5-HT2 receptor affinity (K(i) = 0.26 nM), which is respectively more than 100 and 1000 times higher than its affinity for alpha-1 (K(i) = 38 nM) and D2 (K(i) > 1000 nM) receptors. This compound is a potent orally effective and long lasting 5-HT2 antagonist in the mescaline-induced head-twitches test in mice and rats.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 29679-58-1, Computed Properties of https://www.ambeed.com/products/29679-58-1.html.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com