Chemical Research Letters, April 2021. Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 459-56-3, Name is (4-Fluorophenyl)methanol, molecular formula is C7H7FO, Quality Control of (4-Fluorophenyl)methanol, belongs to isothiazole compound, is a common compound. In a patnet, author is Abd El-Nabi, HA, once mentioned the new application about 459-56-3.
3-Di(methylsulfonyl)methylene-pyrrol-2-one and 2-(1-aryl-5-methoxy-2-oxo-2,3-dihydro-1H-3-pyrrolylidene)malononitrile were obtained from 1-aryl-5-methoxypyrrolones. Aziridine and hydroxylamine reacted with pyrrol-2-one to afford 2,7-diazaspiro[4.4]-nona-3,6-diene and oxime derivatives, respectively. Pyrrolo[2,3-c]isoxazoles or pyrrolo[2,3-c]isothiazole were formed in high yield from oximes depending upon the reaction conditions employed for ring closure. Treatment of pyrrolylidene malononitrile with N-1,N-2-di(4-chlorophenyl)acetamidine in ethyl acetate furnished azepine derivatives in 70-75% yield. (C) 2002 Elsevier Science Ltd. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 459-56-3. Quality Control of (4-Fluorophenyl)methanol.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com