New Advances in Chemical Research, April 2021. Synthetic Route of 35271-74-0, In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. The reactant in an enzyme-catalyzed reaction is called a substrate. 35271-74-0, Name is 3-(4-Chlorophenyl)pentanedioic acid, SMILES is O=C(O)CC(C1=CC=C(Cl)C=C1)CC(O)=O, belongs to isothiazole compound. In a article, author is Shang, Erchang, introduce new discover of the category.
A series of 6-nitro-3-(m-tolylamino) benzo[d] isothiazole 1,1-dioxide analogues were synthesized and evaluated for their inhibition activity against 5-lipoxygenase (5-LOX) and microsomal prostaglandin E-2 synthase (mPGES-1). These compounds can inhibit both enzymes with IC50 values ranging from 0.15 to 23.6 mu M. One of the most potential compounds, 3g, inhibits 5-LOX and mPGES-1 with IC50 values of 0.6 mu M, 2.1 mu M, respectively. (C) 2014 Elsevier Ltd. All rights reserved.
Synthetic Route of 35271-74-0, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect. I hope my blog about 35271-74-0 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com