New Advances in Chemical Research in 2021, Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media. 398489-26-4, Name is tert-Butyl 3-oxoazetidine-1-carboxylate, molecular formula is C8H13NO3, belongs to isothiazole compound. In a document, author is Larson, Gary, introduce the new discover, COA of Formula: C8H13NO3.
A series of isothiazole carboxamidine compounds were synthesized and discovered as novel and selective inhibitors for Chk2. They are not active against the related Chk1 kinase. The structure-activity relationship studies were performed on the scaffold, and enzymatic kinetic analysis showed they are simple ATP competitive inhibitors with K-i values as low as 11 nM for Chk2. Computer modeling studies were employed to comprehend the mechanism of action and SAR of these compounds. (c) 2006 Elsevier Ltd. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 398489-26-4. COA of Formula: C8H13NO3.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com