New Advances in Chemical Research in 2021, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 93-17-4, Name is 3,4-Dimethoxyphenylacetonitrile, molecular formula is C10H11NO2, belongs to isothiazole compound. In a document, author is Zhou, Kaida, introduce the new discover, Formula: C10H11NO2.
An efficient route to diverse 3-sulfonated-2,3-dihydrobenzo[d] isothiazole 1,1-dioxides is achieved through a three-component reaction of 2-ethynylbenzenesulfonamides, DABCO-bis(sulfur dioxide), and aryldiazonium tetrafluoroborates. The corresponding sulfonated benzosultams are produced in moderate to good yields. During the reaction process, the in situ generated arylsulfonyl radical via addition of an aryl radical to sulfur dioxide and the subsequent single electron transfer would be the key steps for the final outcome. DABCO acts as the carrier for single electron transfer, as well as a base to promote the C-N bond formation.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 93-17-4. Formula: C10H11NO2.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com