Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter.2107-69-9, Name is 5,6-Dimethoxy-2,3-dihydro-1H-inden-1-one, SMILES is C1=C2C(=CC(=C1OC)OC)C(CC2)=O, belongs to isothiazole compound. In a document, author is Vicini, Paola, introduce the new discover, COA of Formula: C11H12O3.
2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: Synthesis and structure-activity relationship
2-Heteroarylimino-5-benzylidene-4-thiazolidinones, unsubstituted or carrying hydroxy, methoxy, nitro and chloro groups on the benzene ring, were synthesised and assayed in vitro for their antimicrobial activity against Gram positive and Gram negative bacteria, yeasts and mould. The antimicrobial activity of the 2-benzo[d] thiazolyl-and of the 2-benzo[d] isothiazolyl-imino-5-benzylidene- 4-thiazolidinones is, on the whole, lower in comparison with the high activity detected for the derivatives of the 2-thiazolylimino5- benzylidene-4-thiazolidinone class. Nevertheless most of the benzo[d] thiazole analogues display good inhibition of the growth of Gram positive bacilli and staphylococci, including methicillin-resistant Staphylococcus strains. Among the 2-benzo[d] isothiazole analogues a few derivatives show a strong and selective activity against bacilli. Moreover, it is worth noting that the replacement of the thiazole nucleus for the benzo[d] thiazole bicyclic system in the parent 2-(benzo[d] thiazol-2-ylimino) thiazolidin-4-one leads to significant antifungal properties against both yeasts and moulds, properties not shown by the analogous 2-thiazolyl-and 2-benzo[d] isothiazolyl-imino) thiazolidin-4-ones. The structure-activity relationship of 33 analogues possessing the 2-heteroarylimino-4- thiazolidinone structure is analysed through QSAR models. (C) 2008 Elsevier Ltd. All rights reserved.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2107-69-9 is helpful to your research. COA of Formula: C11H12O3.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com