Discovery of 62476-58-8

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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 62476-58-8, Name is 2-Chloro-3-(trifluoromethyl)aniline, molecular formula is C7H5ClF3N. In an article, author is Seo, Boram,once mentioned of 62476-58-8, Recommanded Product: 2-Chloro-3-(trifluoromethyl)aniline.

Synthesis of Isothiazole via the Rhodium-Catalyzed Transannulation of 1,2,3-Thiadiazoles with Nitriles

A synthetic method for obtaining a wide variety of isothiazoles by the Rh-catalyzed transannulation of 1,2,3-thiadiazoles with alkyl, aryl, and heteroaryl nitriles, which proceeds via an alpha-thiavinyl Rh-carbenoid intermediate, was developed. The results suggest that during its reaction with nitriles, the alpha-thiavinyl carbene acts as an umpolung 1,3-dipole equivalent, in contrast to its behavior during its reaction with alkynes. The developed method was successfully employed to synthesize pentaoligomeric arylene compounds consisting of three benzene and two isothiazole rings.

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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com