Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 2051-95-8, Name is 3-Benzoylpropionicacid, molecular formula is , belongs to isothiazole compound. In a document, author is Soni, Sonam, Application In Synthesis of 3-Benzoylpropionicacid.
Dithioester-enabled chernodivergent synthesis of acids, amides and isothiazoles via C-C bond cleavage and C-O/C N/C-S bond formations under metal- and catalyst-free conditions
An operationally simple and user-friendly process to access privileged scaffolds such as acids, amides and isothiazoles has been devised employing beta-ketodithioesters for the first time. Remarkably, the new protocol involves combination of C-C bond cleavage and C-O/C N/N-S bond formations in one-pot. Aqueous ammonia led to the formation of skeletally distinct amide and isothiazole, whereas aqueous NaOH enabled the formation of aromatic acid near quantitative yield. This practical approach, which can dramatically streamline the synthesis of simple molecules, is highly chemoselective, cost-effective, amenable to gram scale, insensitive to moisture as well as bears high functional group compatibility. (C) 2017 Elsevier Ltd. All rights reserved.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 2051-95-8, in my other articles. Application In Synthesis of 3-Benzoylpropionicacid.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com