Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 29679-58-1, Name is 2-(3-Phenoxyphenyl)propanoic acid, molecular formula is , belongs to isothiazole compound. In a document, author is MALLERON, JL, Quality Control of 2-(3-Phenoxyphenyl)propanoic acid.
NAPHTHOSULTAM DERIVATIVES – A NEW CLASS OF POTENT AND SELECTIVE 5-HT2 ANTAGONISTS
A series of 2-(aminoalkyl)naphth[1,8-cd]isothiazole 1,1-dioxides was synthesized and examined in various receptor binding tests. Most compounds demonstrated high affinity for the 5-HT2 receptor with moderate to high selectivity. A member of this series, compound 24 (RP 62203), displays high 5-HT2 receptor affinity (K(i) = 0.26 nM), which is respectively more than 100 and 1000 times higher than its affinity for alpha-1 (K(i) = 38 nM) and D2 (K(i) > 1000 nM) receptors. This compound is a potent orally effective and long lasting 5-HT2 antagonist in the mescaline-induced head-twitches test in mice and rats.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 29679-58-1, in my other articles. Quality Control of 2-(3-Phenoxyphenyl)propanoic acid.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com