In an article, author is STRATMANN, K, once mentioned the application of 2144-08-3, Name is 2,3,4-Trihydroxybenzaldehyde, molecular formula is C7H6O4, molecular weight is 154.1201, MDL number is MFCD00003325, category is isothiazole. Now introduce a scientific discovery about this category, Name: 2,3,4-Trihydroxybenzaldehyde.
AULOSIRAZOLE, A NOVEL SOLID TUMOR SELECTIVE CYTOTOXIN FROM THE BLUE-GREEN-ALGA AULOSIRA-FERTILISSIMA
Aulosirazole, the major cytotoxin in the blue-green alga (cyanobacterium) Aulosira fertilissima Ghose (UH strain DO-8-1), shows solid tumor selective activity in the Corbett assay. Its structure has been determined to be 5-hydroxy-3-methoxynaphtho[2,3-d]-1,2-thiazole-4,9-dione by a combination of spectroscopic, notably NMR, and X-ray crystallographic methods. The carbon skeleton and the juglone nature of 1 was determined by two-dimensional H-1-C-13 NMR correlation spectral analysis and one-dimensional C-13-C-13 decoupling experiments, the latter on the C-13-enriched cytotoxin. The presence of an isothiazole ring and the position of attachment for the juglone system was rigorously established by an X-ray crystallographic study.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com