Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Computed Properties of C11H8O, 66-77-3, Name is 1-Naphthaldehyde, SMILES is O=CC1=C2C=CC=CC2=CC=C1, belongs to isothiazole compound. In a document, author is Dyachenko, Maksim S., introduce the new discover.
4-Amino-2,3-dihydro-lambda 1(6)-isothiazole-1,1-dioxides and their chemical properties evaluation
The reactivity of the 4-amino-2,3-dihydro-1H-lambda 1(6)-isothiazole-1,1-dioxide (beta-amino-gamma-sultam) framework has not been studied sufficiently. Here we describe the chemical properties of this heterocyclic system toward electrophiles on spiranic and non-spiranic substrates. A variety of C-electrophiles (acetic anhydride, benzoyl chloride, DMFDMA, 4,4-dimethoxybutan-2-one) and heteroatom electrophiles (bromine, nitrosyl acetate) have been explored. Both the C-5 and 4-amino positions of the beta-amino-gamma-sultam system are able to undergo electrophilic reactions. Heteroatom electrophiles attack the C-5 position, whereas carbo-electrophiles affect the amino group. beta-Amino-gamma-sultams also were used as starting compounds for the synthesis of 6- or 7-substituted 1 lambda(6)-isothiazolo[4,5-b]pyridine-1,1-dioxides through condensation reaction and palladium-catalyzed oxidative coupling.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 66-77-3. Computed Properties of C11H8O.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com