Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.611-14-3, Name is 1-Ethyl-2-methylbenzene, SMILES is CC1=CC=CC=C1CC, belongs to isothiazole compound. In a document, author is Christoforou, Irene C., introduce the new discover, Quality Control of 1-Ethyl-2-methylbenzene.
1,2,3-Dithiazole chemistry in heterocyclic synthesis
The chemistry of various 5H-1,2,3-dithiazoles is investigated with emphasis on assisted ring opening and ring closure reactions leading to new heterocycles. Thus on treatment with catalytic tetraalkylammonium iodide N-(2-chloropyrid-3-yl)- and N-(4-chloropyrid-3-yl)-4-chloro-1,2,3-dithiazol- 5H-imines 19 and 20 give thiazolo[ 5,4-b] pyridine-2-carbonitrile 16 and thiazolo[ 4,5-c] pyridine-2-carbonitrile 17 respectively. Similar treatment of bisdithiazoles 29 and 30 afford high yielding routes to 1,3,4-thiadiazole- 2,5-dicarbonitrile 31 and thiazole-2,4,5-tricarbonitrile 32 respectively. N-(Pyrid-3-yl)-4-chloro- 1,2,3-dithiazol-5H-imine 36 reacts with secondary alkylamines to give as main product pyrido[ 2,3-d] pyrimidines 37 and several minor byproducts including a deep green quinoidal 2,2′-bithiazole 40. Dithiazolylidenacetonitriles 43 react with either anhydrous HBr or tetraalkylammonium chloride to afford a series of 3-halo-4-substituted- isothiazole-5-carbonitriles 45 and 52 respectively. The reactions of dithiazoles 43 with tetraalkylammonium chloride are complicated owing to the formation of isothiazolopentathiepin-8- carbonitrile 53, isothiazolodithiin-4,5,7-tricarbonitrile 54, tetracyanothiophene 56 and an unidentified compound 55 whose possible structures are proposed. The mechanistic rationales for the formation of the identified products are proposed.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 611-14-3. Quality Control of 1-Ethyl-2-methylbenzene.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com