Electric Literature of 519-73-3, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 519-73-3, Name is Triphenylmethane, SMILES is C(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3, belongs to isothiazole compound. In a article, author is Banerjee, Abhisek, introduce new discover of the category.
Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation
The synthesis and structure-activity relationship studies of isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors are discussed. The pharmacokinetic profile of 10 and 21 with adequate CNS penetration, required for in vivo Parkinson’s disease models, are disclosed. (C) 2012 Elsevier Ltd. All rights reserved.
Electric Literature of 519-73-3, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 519-73-3 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com