Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 104-66-5, Name is 1,2-Diphenoxyethane, molecular formula is C14H14O2. In an article, author is Greig, IR,once mentioned of 104-66-5, Category: isothiazole.
Synthesis of cyclic sulfonamides through intramolecular Diels-Alder reactions
[GRAPHICS] Substituted 2,3,3a,4,5,7a-hexahydrobenzo[D]isothiazole 1,1-dioxides and 3,4,4a,5,6,8a-hexahydro-2H-benzo[e][1,2]thiazine 1,1-dioxides, novel cyclic sulfonamides, were synthesized by the thermal Diels-Alder reaction of triene derivatives of buta-1,3-diene 1-sulionic acid amide, The stereochemical outcome of the reaction was determined by NMR spectroscopy and X-ray crystallographic analysis. This chemistry has been used for the synthesis of 2-(4-chlorobenzyl)-5-(1H-imidazol-4-yl)-2,3,3a,4,5,7a-hexahydrobenzo[d]isothiazole 1,1-dioxide, a histamine H-3 receptor antagonist.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com