Synthetic Route of 28562-53-0, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 28562-53-0, Name is 4-Acetoxy-2-azetidinone, SMILES is CC(OC1NC(C1)=O)=O, belongs to isothiazole compound. In a article, author is Hamama, W. S., introduce new discover of the category.
SYNTHESIS AND ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF SIMPLE SACCHARIN DERIVATIVES WITH N-BASIC SIDE CHAINS
A new class of N-basic side chains was obtained from 2,3-dihydro-2H-3-oxobenzo[d] isothiazole and aliphatic or aromatic aldehydes. Secondary amines (morpholine, N-methylpiperazine and ethyl isonipecotate) afforded tertiary N-basic side chains (4-6), while dibasic secondary amines (such as piperazine) gave bis-tertiary N-basic side chains (2). On the other hand, the use of mono-or dibasic primary amines namely; aniline, anisidine, phenyl hydrazine, o-hydroxy benzoic acid hydrazide, hydrazine hydrate, and ethylenediamine (instead of secondary amines) afforded secondary N-basic side chain as mono component or as bis component 7a-c, 9a-c, 11 and 12a-c. In addition, secondary Mannich base was synthesized via Michael addition to the corresponding aldimine. The new compounds were investigated for antioxidant and antimicrobial activities. Compounds 2, 7c and 12a exhibited significant antimicrobial activity, whereas compounds 7a, 7b, 9b, 9c and 11 exhibited high antioxidant activity as compared to ascorbic acid, These compounds showed the best protective effect against DNA damage induced by bleomycin.
Synthetic Route of 28562-53-0, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 28562-53-0 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com