Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, COA of Formula: C16H17NO, 18621-17-5, Name is 1-Benzhydrylazetidin-3-ol, SMILES is C3=C(C(N1CC(O)C1)C2=CC=CC=C2)C=CC=C3, belongs to isothiazole compound. In a document, author is Liu, Bei-Bei, introduce the new discover.
Cascade Trisulfur Radical Anion (S-3(center dot-)) Addition/Electron Detosylation Process for the Synthesis of 1,2,3-Thiadiazoles and Isothiazoles
Trisulfur radical anion (S-3(center dot-)) mediated reactions with in situ formed azoalkenes and alpha,beta-usaturated N-sulfonylimines for the construction of 1,2,3-thiadiazoles and isothiazoles has been developed. S-3(center dot-) is in situ generated from potassium sulfide in DMF. These two approaches provide a new, safe, and simple way to construct 4-subsituted 1,2,3-thiadiazoles, 5-subsituted 1,2,3-thiadiazoles, and isothiazole in good yields. The reactions include the formation of the new C-S and N-S bonds via S-3(center dot-) addition and electron detosylation under mild conditions.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 18621-17-5. COA of Formula: C16H17NO.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com