Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 22884-95-3, Name is 3,4-Dimethylbenzonitrile, molecular formula is C9H9N, belongs to isothiazole compound. In a document, author is Mihara, Gen, introduce the new discover, COA of Formula: C9H9N.
Rhodium-Catalyzed Annulative Coupling of Isothiazoles with Alkynes through N-S Bond Cleavage
A Rh(III)-catalyzed annulative coupling of 3,5-diarylisothiazoles and alkynes is reported. The N-S bond in the isothiazole ring acts as an internal oxidant to regenerate the Rh(III) species in combination with an external Cu(II) oxidant, and the corresponding 1:2 coupling products are obtained. The remarkable difference in the reaction outcome between isothiazoles and the relevant isoxazoles has been investigated by DFT calculations, revealing that the relative stability of the enolate intermediates dictates the product selectivity.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 22884-95-3. COA of Formula: C9H9N.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com