One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 3034-86-4, Name is Methyl 4-ethynylbenzoate, formurla is C10H8O2. In a document, author is Incerti, Matteo, introducing its new discovery. Computed Properties of C10H8O2.
Investigation of the Reaction between 3-Benzisothiazolones, an Isoindole Isoster and Activated Acetylenes: Synthesis of Heterocyclic Backbones for Building Bioactive Molecules
Investigation of the reaction between benzo[d]isothiazol-3-one, 2-aminobenzo[d]isothiazol-3-one, its isoster 2-aminoisoindolin-1-one, and activated acetylenes, in the presence of triphenylphosphine, led us to synthesize novel heterocyclic compounds that could be attractive for the building of biologically active molecules. A one-pot PPh3-promoted tandem reaction, with acetylene dicarboxylates and dibenzoylacetylene, afforded new tricyclic pyrazolo-fused benzisothiazoles. The PPh3-promoted reaction between benzisothiazolones and methyl propiolate afforded 1,4-benzothiazepine-5-one derivatives, via an isothiazole ring expansion. These studies are providing additional insights in benzisothiazolone chemistry and describe simple and original synthetic accesses to novel derivatives.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com