In an article, author is Ivanova, Jekaterina, once mentioned the application of 39515-51-0, Safety of 3-Phenoxybenzaldehyde, Name is 3-Phenoxybenzaldehyde, molecular formula is C13H10O2, molecular weight is 198.2173, MDL number is MFCD00003353, category is isothiazole. Now introduce a scientific discovery about this category.
X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors
1-N-Alkylated-6-sulfamoyl saccharin derivatives were prepared and assayed as carbonic anhydrase inhibitors (CAIs). During X-ray crystallographic experiments an unexpected hydrolysis of the isothiazole ring was evidenced which allowed us to prepare highly potent enzyme inhibitors with selectivity for some isoforms with medical applications.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com