Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Review, the author is Dyachenko, Vladimir D. and a compound is mentioned, Recommanded Product: Isothiazole, Isothiazole, introducing its new discovery. Recommanded Product: Isothiazole
Cyanothioacetamide: A polyfunctional reagent with broad synthetic utility
The review integrates and analyzes the published data on the chemical reactivity of a-cyanothioacetamide, a convenient starting compound for the preparation of activated alkenes, functionally substituted pyrans, thiopyrans, pyridines, thiophenes, pyrroles, quinolines, isoquinolines, pyrimidines, thienopyrroles, pyrazolopyridines, pyridothienopyrimidines and pyrimidothienodiazines. The relatively small a-cyanothioacetamide molecule has several reaction centres. Nucleophilic reactions of the methylene group are covered most extensively, including the Thorpe reaction; reactions with diazonium salts, azides, iso(thio)cyanates and nitroso compounds; nucleopilic substitution; Knoevenagel condensation; Michael reaction; and multicomponent syntheses. Separate parts of the review are devoted to nucleophilic reactions involving the thiocarbonyl and amino groups and electrophilic reactions involving thiocarbonyl and nitrile groups. The focus is on the publications of the last 15 years.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: Isothiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 288-16-4, in my other articles.
Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com