Reference of 27148-03-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide,introducing its new discovery.
Synthesis of 1,2,3-Benzothiadiazine-1,1 -dioxide Derivatives and their Pharmacological Properties
Formation of 4-(Sub)-amino-1,2,3-benzothiadiazine-1,1-dioxide was established by earlier reported base catalysed ring expansion reaction. Products thus obtained, were stable in aqueous alkaline and acidic medium and on alkylation/acylation furnished 4-amino derivative (4, 5) exclusively, instead of 2-N-derivative (3). Preliminary pharmacological screening was done and the results were positive.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Reference of 27148-03-4, you can also check out more blogs about27148-03-4
Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com