The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.category: isothiazole, Name is Isothiazole-3-carboxylic acid, molecular formula is C4H3NO2S, category: isothiazole. In a Article, authors is Galatsis, Paul£¬once mentioned of category: isothiazole
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold
Leucine rich repeat kinase 2 (LRRK2) has been genetically linked to Parkinson’s disease (PD). The most common mutant, G2019S, increases kinase activity, thus LRRK2 kinase inhibitors are potentially useful in the treatment of PD. We herein disclose the structure, potential ligand-protein binding interactions, and pharmacological profiling of potent and highly selective kinase inhibitors based on a triazolopyridazine chemical scaffold.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, category: isothiazole, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 4576-90-3
Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com